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Auditory Event-Related Potentials To Speech And Acoustic Stimulus In Premature Infants With Periventricular Leukomalacia |
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Gloria Nelida Avecilla-Ramirez - Instituto de Neurobiología, UNAM
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Thalía Harmony - Instituto de Neurobiología, UNAM
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Melissa Calderon - Instituto de Neurobiología, UNAM
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Eneida Porras-Kattz - Instituto de Neurobiología, UNAM
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Josefina Ricardo-Garcell - Instituto de Neurobiología, UNAM
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Antonio Fernández-Bouzas - Instituto de Neurobiología, UNAM
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SRCLD Year: |
2012 |
Presentation Type: |
Poster Presentation |
Poster Number: |
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Presentation Time: |
(na) |
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- Neuro Development/Language |
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Periventricular Leukomalacia (PVL) is the predominant form of brain white matter lesion in preterm and newborn infants, and represents the major cause of long-term neurological and cognitive disabilities in surviving infants. Te aim of this work is to correlate the Event Related Potentials recorded at early age with the posterior development of language in infants with PVL antecedents and in healthy infants. In a first stage, we examined recordings of PREs in 15 infants with PVL (1.5 months) and 14 healthy control infants (1.5 months) listening phonetic and acoustic stimuli. In the second stage, we correlate latency and amplitude of P350 component in response to syllables in every infant with their results in language comprehension and production at 14 months. We found a positive linear correlation between amplitude and comprehension and between amplitude and production, and a negative linear correlation between latency and comprehension. These results show that ERPs in response to syllables could be used as a predictive factor of language development in infants at risk of cognitive impairments.
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