SRCLD Presentation Details
  Title  
       
    A longitudinal case study of a child with Mosaic Trisomy 22: language, cognitive, and behavioral outcomes  
Author(s)
Sarah Fulton - Department of Pediatrics, Case Western Reserve University
Barbara Lewis - Pediatrics, Case Western Reserve University
Lynn T. Singer - Department of General Medical Sciences, Case Western Reserve University
Daniel Rosenbaum - Pediatrics, Case Western Reserve University
Elizabeth Short - Psychology, Case Western Reserve University
Nancy Klein - Department of Education, Cleveland State University
Meeyoung O. Min - Pediatrics, Case Western Reserve University
Suchitra Nelson - School of Dentistry, Case Western Reserve University
Carolyn Kercsmar - Pediatrics, Case Western Reserve University
Jill Baley - Pediatrics, Case Western Reserve University

SRCLD Info
SRCLD Year: 2006
Presentation Type: Poster Presentation
Poster Number:
Presentation Time: (na)
Categories
- Genetics/Language Development
Abstract
As genetic screenings become routine, more children with genetic syndromes are identified. However, most reports on syndromes fail to describe detailed language, cognitive and behavioral outcomes that would be useful to parents and professionals in planning educational programs. The goal of this presentation is to describe the developmental course of a boy with a rare chromosomal disorder, Trisomy 22. The child was assessed from birth to 14 years of age on a battery of language, cognitive and behavioral tests at 6 time points. Results showed a stable pattern of IQ (full scale=55) across time points, with relative strengths in processing speed (standard score =70) and verbal IQ (standard score=67) and a weakness in working memory. Other strengths relative to his full scale IQ are receptive language and social skills. Achievements in math and reading and motor skills improved with age but were significantly below age expectations. These findings highlight the need for careful clinical case studies of children with syndromes and description of strengths and weaknesses specific to a syndrome.